SCHEMBL68683

SCHEMBL68683

Cc1cc(Br)c(O)c(Cc2cc(C)cc(Br)c2O)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AMY1A P0DUB6 1/20 0.53
HSPA5 P11021 1/20 0.53
HIF1A Q16665 4/20 0.52
CYP2C9 P11712 3/20 0.52
CYP2C19 P33261 3/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA4 P22748 2/20 0.46
CA6 P23280 2/20 0.46
CYP2D6 P10635 2/20 0.46
HSD17B10 Q99714 2/20 0.46
PTPN1 P18031 3/20 0.45
CYP3A4 P08684 2/20 0.39
TSHR P16473 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
SELL P14151 1/20 0.39
SELP P16109 1/20 0.39
SELE P16581 1/20 0.39
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9560149 0.86 SHBG (0.45) AMY1AHSPA5HIF1ACYP2C9CYP2C19
SCHEMBL1502445 0.80 CYP3A4 (0.58) HIF1ASMN1; SMN2CA1CA2CA4
SCHEMBL29400422 0.79 AMY1A (0.61) AMY1AHSPA5HIF1ACYP2C9CYP2C19
SCHEMBL210506 0.79 AMY1A (0.61) AMY1AHSPA5HIF1ACYP2C9CYP2C19
SCHEMBL1482608 0.79 AMY1A (0.61) AMY1AHSPA5HIF1ACYP2C9CYP2C19
SCHEMBL23887046 0.78 ERN1 (0.39) AMY1AHSPA5HIF1ACYP2C9CYP2C19
SCHEMBL18896367 0.78 ALOX5 (0.44) SMN1; SMN2CYP3A4TSHRTDP1ALOX5
SCHEMBL29003828 0.78 CYP3A4 (0.42) AMY1AHSPA5HIF1ACYP2C9CYP2C19
SCHEMBL4219327 0.78 GAA (0.43) HSD17B10PTPN1ALOX5PTGS2ALDH1A1
Methane SCHEMBL21814228 0.78 CYP3A4 (0.55) HIF1ASMN1; SMN2CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2714763-B1 EPOXY RESINS WITH HIGH THERMAL STABILITY AND TOUGHNESS HUNTSMAN ADVANCED MAT AMERICAS LLC (US) 2017-03-01 EP disclosed
US-9051415-B2 Epoxy resins with high thermal stability and toughness HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2015-06-09 US disclosed
US-9051415-B2 Epoxy resins with high thermal stability and toughness HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2015-06-09 US disclosed
US-9051498-B2 Epoxy resins with high thermal stability and toughness HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2015-06-09 US disclosed
US-9051498-B2 Epoxy resins with high thermal stability and toughness HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2015-06-09 US disclosed
US-20140296447-A1 Epoxy Resins With High Thermal Stability and Toughness Huntsman Advanced Materials Americans LLC (US) 2014-10-02 US disclosed
US-20140296447-A1 Epoxy Resins With High Thermal Stability and Toughness Huntsman Advanced Materials Americans LLC (US) 2014-10-02 US disclosed
US-20140069583-A1 Epoxy Resins With High Thermal Stability and Toughness HUNTSMAN ADVANCED MATERIALS AMERICAS LLC 2014-03-13 US disclosed
US-20140069583-A1 Epoxy Resins With High Thermal Stability and Toughness HUNTSMAN ADVANCED MATERIALS AMERICAS LLC 2014-03-13 US disclosed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
US-20100285269-A1 BASALT PARTICLE-CONTAINING COMPOSITIONS AND ARTICLES FOR PROTECTIVE COATINGS AND BALLISTIC SHIELD MATS/TILES/PROTECTIVE BUILDING COMPONENTS U.S. WIND FARMING, INC. (US) 2010-11-11 US disclosed
US-20100285269-A1 BASALT PARTICLE-CONTAINING COMPOSITIONS AND ARTICLES FOR PROTECTIVE COATINGS AND BALLISTIC SHIELD MATS/TILES/PROTECTIVE BUILDING COMPONENTS U.S. WIND FARMING, INC. (US) 2010-11-11 US disclosed
US-20100012004-A1 Basalt particle-containing compositions and articles for protective coatings and ballistic shield mats/tiles/protective building components U.S. WIND FARMING INC. (US) 2010-01-21 US disclosed
US-20090067924-A1 HYDROCARBON-ADSORBING POROUS PAVEMENT STRUCTURE KAUL CORPORATION (US) 2009-03-12 US disclosed
US-20090067924-A1 HYDROCARBON-ADSORBING POROUS PAVEMENT STRUCTURE KAUL CORPORATION (US) 2009-03-12 US disclosed
US-20070224401-A1 Basalt particle-containing articles for ballistic shield mats/tiles/protective building components U.S. WIND FARMING INC. (US) 2007-09-27 US disclosed
US-20070224401-A1 Basalt particle-containing articles for ballistic shield mats/tiles/protective building components U.S. WIND FARMING INC. (US) 2007-09-27 US disclosed
US-20070154643-A1 Extrusion coating compositions and method VALSPAR SOURCING, INC. (US) 2007-07-05 US disclosed
US-20070154643-A1 Extrusion coating compositions and method VALSPAR SOURCING, INC. (US) 2007-07-05 US disclosed