Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | HCRTR1 | O43613 | 10/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 10/20 | 0.44 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1827356 | 0.78 | RIPK1 (0.45) | BRD4ALDH1A1MAPT | |
| SCHEMBL4427165 | 0.76 | BRD4 (0.47) | BRD4HCRTR1HCRTR2FFAR2CYP11B2 | |
| SCHEMBL26772897 | 0.68 | CHRNB4 (0.59) | BRD4CYP11B2 | |
| SCHEMBL31229667 | 0.67 | CHRNB2 (0.53) | BRD4HCRTR1HCRTR2CYP11B2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7688522 | 0.67 | CHRNB4 (0.57) | BRD4CYP11B2 | |
| SCHEMBL1830591 | 0.66 | SLC18A3 (0.46) | HCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL621942 | 0.65 | BRD4 (0.47) | BRD4HCRTR1HCRTR2ADRA2AADRA1D | |
| SCHEMBL13454056 | 0.65 | TP53 (0.58) | BRD4HCRTR1HCRTR2CYP11B2NPC1 | |
| SCHEMBL24774528 | 0.65 | CYP11B2 (0.46) | BRD4HCRTR1HCRTR2CYP11B2 | |
| SCHEMBL23323089 | 0.65 | CYP11B2 (0.49) | BRD4HCRTR1HCRTR2CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5248736-A | Reacting end groups of conjugated diene polymer with carbon dioxide or carbon disulfide and then with pyrrolidone | NIPPON ZEON CO., LTD. (JP) | 1993-09-28 | — | — | US | disclosed |