SCHEMBL956150

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2745435	1.00	AKR1C3 (0.46)	AKR1C3AKR1C2PTGS1AKR1C1SLC22A12
	SCHEMBL1008197	0.88	MAPK1 (0.41)	SLC22A12KMT2ASMN1; SMN2FFAR1
	SCHEMBL1008990	0.85	AKR1C3 (0.50)	AKR1C3AKR1C2PTGS1AKR1C1KMT2A
	SCHEMBL2745203	0.84	PTGS1 (0.58)	AKR1C3AKR1C2PTGS1SLC22A12KMT2A
	SCHEMBL2381049	0.84	KMT2A (0.60)	KMT2ASMN1; SMN2ALOX5
	SCHEMBL954605	0.84	PTGS1 (0.58)	AKR1C3AKR1C2PTGS1SLC22A12KMT2A
	SCHEMBL1634518	0.83	FFAR1 (0.51)	SLC22A12KMT2ASMN1; SMN2FFAR1
	SCHEMBL10455351	0.81	KMT2A (0.57)	AKR1C3AKR1C2PTGS1AKR1C1KMT2A
	SCHEMBL14406985	0.80	SLC22A12 (0.41)	PTGS1SLC22A12KMT2ASMN1; SMN2FFAR1
	SCHEMBL1135051	0.79	MAPK1 (0.39)	SLC22A12KMT2ASMN1; SMN2FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.