Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | KDM6B | O15054 | 2/20 | 0.44 |
| ▸ | KDM5C | P41229 | 2/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.44 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TET3 | O43151 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | ASPH | Q12797 | 1/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.41 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.41 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL930636 | 0.81 | JMJD6 (0.57) | KDM5CKDM4CSMN1; SMN2KDM5AKDM5B | |
| SCHEMBL29466587 | 0.81 | JMJD6 (0.57) | KDM5CKDM4CSMN1; SMN2KDM5AKDM5B | |
| SCHEMBL9561789 | 0.80 | TSHR (0.47) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL30065796 | 0.79 | KDM4E (0.62) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL70350 | 0.79 | KDM4E (0.62) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL8406007 | 0.78 | JMJD6 (0.59) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL27684580 | 0.78 | ALDH1A1 (0.60) | KDM4EALDH1A1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL9345745 | 0.77 | JMJD6 (0.44) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL1977297 | 0.77 | JMJD6 (0.44) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL12035659 | 0.76 | TSHR (0.55) | TSHRALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11045407-B2 | Process for treating keratin fibres with a pyridinedicarboxylic acid compound | L'OREAL (FR) | 2021-06-29 | — | — | US | disclosed |
| US-10857087-B2 | Process for treating keratin fibres with a polysaccharide and a pyridinedi-carboxylic acid compound | L'OREAL (FR) | 2020-12-08 | — | — | US | disclosed |
| WO-2016142635-A1 | METHOD FOR THE COSMETIC TREATMENT OF THICK HAIR WITH A PYRIDINE DICARBOXYLIC ACID COMPOUND | L'OREAL (FR) | 2016-09-15 | — | — | WO | disclosed |
| US-20160228346-A1 | PROCESS FOR TREATING KERATIN FIBRES WITH A POLYSACCHARIDE AND A PYRIDINEDI-CARBOXYLIC ACID COMPOUND | L'OREAL (FR) | 2016-08-11 | — | — | US | disclosed |
| US-20160228346-A1 | PROCESS FOR TREATING KERATIN FIBRES WITH A POLYSACCHARIDE AND A PYRIDINEDI-CARBOXYLIC ACID COMPOUND | L'OREAL (FR) | 2016-08-11 | — | — | US | disclosed |
| US-20160213587-A1 | PROCESS FOR TREATING KERATIN FIBRES WITH A PYRIDINEDICARBOXYLIC ACID COMPOUND | L'OREAL (FR) | 2016-07-28 | — | — | US | disclosed |
| US-20160213587-A1 | PROCESS FOR TREATING KERATIN FIBRES WITH A PYRIDINEDICARBOXYLIC ACID COMPOUND | L'OREAL (FR) | 2016-07-28 | — | — | US | disclosed |
| WO-2015036477-A1 | PROCESS FOR TREATING KERATIN FIBRES WITH A PYRIDINEDICARBOXYLIC ACID COMPOUND | L'OREAL (FR) | 2015-03-19 | — | — | WO | disclosed |
| WO-2015036476-A1 | PROCESS FOR TREATING KERATIN FIBRES WITH A POLYSACCHARIDE AND A PYRIDINEDI-CARBOXYLIC ACID COMPOUND | L'OREAL (FR) | 2015-03-19 | — | — | WO | disclosed |
| US-5260323-A | 2,4- and 2,5-substituted pyridine-N-oxides, processes for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11045407-B2 | Process for treating keratin fibres with a pyridinedicarboxylic acid compound | KRT18, CUTA, HKDC1 | KDM4E 45/4885KDM6B 54/4885KDM5C 15/4885 |
| US-20160228346-A1 | PROCESS FOR TREATING KERATIN FIBRES WITH A POLYSACCHARIDE AND A PYRIDINEDI-CARBOXYLIC ACID COMPOUND | KRT18, HKDC1, PHYKPL | KDM4E 215/4885KDM6B 109/4885KDM5C 6/4885 |
| US-20160213587-A1 | PROCESS FOR TREATING KERATIN FIBRES WITH A PYRIDINEDICARBOXYLIC ACID COMPOUND | KRT18, CUTA, HKDC1 | KDM4E 45/4885KDM6B 54/4885KDM5C 15/4885 |
| US-10857087-B2 | Process for treating keratin fibres with a polysaccharide and a pyridinedi-carboxylic acid compound | KRT18, HKDC1, PHYKPL | KDM4E 215/4885KDM6B 109/4885KDM5C 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.