SCHEMBL9562001

SCHEMBL9562001

COC(=O)C(C)(C)O.C[SiH3]

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.44
ALDH1A1 P00352 3/20 0.40
TSHR P16473 2/20 0.40
SRC P12931 1/20 0.35
KCNN4 O15554 1/20 0.34
KEAP1 Q14145 1/20 0.30
NFE2L2 Q16236 1/20 0.30
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL134110 0.94
Methyl Alcohol SCHEMBL28262055 0.91 DGAT1 (0.46) DGAT1ALDH1A1TSHRSRCKCNN4
Bicarbonate SCHEMBL14689679 0.88 ALDH1A1 (0.47) DGAT1ALDH1A1TSHRSRCKCNN4
Propanol SCHEMBL28070561 0.85 DGAT1 (0.38) DGAT1ALDH1A1TSHRSRCKCNN4
SCHEMBL6863429 0.78 ALDH1A1 (0.43) DGAT1ALDH1A1TSHRSRCKCNN4
Methacrylic Acid SCHEMBL12100845 0.78 ALDH1A1 (0.42) DGAT1ALDH1A1TSHRSRCKCNN4
SCHEMBL28176663 0.78 PKM (0.43) DGAT1ALDH1A1TSHR
SCHEMBL15114674 0.77 DGAT1 (0.44) DGAT1ALDH1A1TSHRSRCKCNN4
SCHEMBL8197999 0.76 SMN1; SMN2 (0.37) DGAT1ALDH1A1TSHR
SCHEMBL7019538 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5250106-A Process for water-repellent impregnation of masonry WACKER-CHEMIE GMBH (DE) 1993-10-05 US disclosed