Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 3/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9562026 | 1.00 | CYP2C9 (0.34) | CYP2C9LMNAALDH1A1MAPTRAB9A | |
| SCHEMBL9457329 | 0.89 | RAB9A (0.39) | CYP2C9LMNAALDH1A1MAPTRAB9A | |
| SCHEMBL9191317 | 0.89 | RAB9A (0.39) | CYP2C9LMNAALDH1A1MAPTRAB9A | |
| SCHEMBL9417019 | 0.86 | LMNA (0.43) | CYP2C9LMNAALDH1A1MAPTRAB9A | |
| SCHEMBL9561526 | 0.83 | THRB (0.33) | THRBPTGER2 | |
| SCHEMBL6896856 | 0.82 | CYP2C9 (0.46) | CYP2C9LMNAALDH1A1MAPTRAB9A | |
| SCHEMBL8021886 | 0.82 | RAB9A (0.39) | CYP2C9LMNAALDH1A1MAPTRAB9A | |
| SCHEMBL9562081 | 0.82 | THRB (0.43) | MAPTRAB9ATHRBNPC1SMN1; SMN2 | |
| SCHEMBL9562123 | 0.81 | MAPT (0.33) | CYP2C9LMNAALDH1A1MAPTMEN1 | |
| SCHEMBL9562117 | 0.81 | MAPT (0.33) | CYP2C9LMNAALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5232624-A | Components of tilted smectic liquid-crystalline phases | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-08-03 | — | — | US | disclosed |