Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9686196 | 0.81 | MAPT (0.61) | MAPTNPC1L3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL9563508 | 0.81 | KEAP1 (0.54) | MAPTMAPK1HTTL3MBTL1SMN1; SMN2 | |
| Acetic Acid SCHEMBL6271336 | 0.78 | L3MBTL1 (0.47) | MAPTNPC1HTTL3MBTL1SMN1; SMN2 | |
| SCHEMBL9563516 | 0.77 | SMN1; SMN2 (0.74) | MAPTNPC1HTTL3MBTL1SMN1; SMN2 | |
| SCHEMBL5383825 | 0.76 | MAPT (0.73) | MAPTNPC1MAPK1HTTL3MBTL1 | |
| SCHEMBL31366618 | 0.76 | MAPT (0.73) | MAPTNPC1MAPK1HTTL3MBTL1 | |
| SCHEMBL2353757 | 0.75 | ALDH1A1 (0.58) | NPC1L3MBTL1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL9650611 | 0.73 | PARP1 (0.50) | MAPTL3MBTL1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL4683307 | 0.73 | ALDH1A1 (0.50) | NPC1L3MBTL1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL13328057 | 0.73 | TPMT (0.47) | MAPTNPC1L3MBTL1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552665-A1 | Pyrrolylbenzodiazepinones and medicines containing them | F. HOFFMANN-LA ROCHE AG (CH) | 1993-07-28 | — | — | EP | disclosed |