Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564299 | 0.84 | RAB9A (0.44) | LMNAALDH1A1RAB9ATHRBTP53 | |
| SCHEMBL8553021 | 0.73 | LMNA (0.52) | LMNAALDH1A1RAB9ATHRBTP53 | |
| SCHEMBL9564315 | 0.73 | CHRNA7 (0.33) | — | |
| Nitrobenzene SCHEMBL8808923 | 0.71 | ALDH1A1 (0.84) | LMNAALDH1A1TP53MAPTPOLB | |
| Nitrobenzene SCHEMBL16892591 | 0.71 | ALDH1A1 (0.84) | LMNAALDH1A1TP53MAPTPOLB | |
| Nitrobenzene SCHEMBL28721943 | 0.71 | ALDH1A1 (0.84) | LMNAALDH1A1TP53MAPTPOLB | |
| SCHEMBL8967906 | 0.70 | ICMT (0.46) | LMNAALDH1A1RAB9ATHRBMAPT | |
| SCHEMBL8967712 | 0.70 | MAPT (0.47) | LMNAALDH1A1RAB9ATHRBSIGMAR1 | |
| Nitrobenzene SCHEMBL2358164 | 0.69 | ALDH1A1 (1.00) | LMNAALDH1A1TP53POLBMEN1 | |
| Nitrobenzene SCHEMBL1330714 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543307-A2 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1993-05-26 | — | — | EP | disclosed |