Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564345 | 0.77 | KDR (0.34) | RAB9AMAPTNPC1KMT2AKDR | |
| SCHEMBL9564349 | 0.77 | KDR (0.34) | RAB9AMAPTNPC1KMT2AKDR | |
| SCHEMBL9564386 | 0.76 | DAO (0.41) | DAORAB9AMAPTSMN1; SMN2HPGD | |
| SCHEMBL10874394 | 0.71 | MAPT (0.48) | RAB9AMAPTSMN1; SMN2NPC1HPGD | |
| SCHEMBL9564372 | 0.69 | KMT2A (0.43) | DAORAB9AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL9564365 | 0.69 | KMT2A (0.43) | DAORAB9AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL9564382 | 0.69 | KMT2A (0.44) | GSK3BDAORAB9AMAPTSMN1; SMN2 | |
| SCHEMBL9564369 | 0.69 | ALDH1A1 (0.49) | GSK3BMAPTSMN1; SMN2MAPK1KMT2A | |
| SCHEMBL9564408 | 0.68 | ALDH1A1 (0.39) | RAB9ASMN1; SMN2NPC1L3MBTL1KDM4E | |
| SCHEMBL9591168 | 0.67 | DAO (0.61) | GSK3BDAORAB9AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563686-A1 | Utilization of 3 substituted amino isoxazole derivatives against endoparasites, new 3 substituted amino isoxazols and process for their preparation | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |