Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10874394 | 0.77 | MAPT (0.48) | GAASMN1; SMN2ALDH1A1RAB9AMEN1 | |
| SCHEMBL9564362 | 0.76 | GSK3B (0.42) | DAOL3MBTL1GAASMN1; SMN2RAB9A | |
| SCHEMBL9564422 | 0.75 | CES2 (0.40) | DAORAB9AMEN1KMT2AMAPT | |
| SCHEMBL9564413 | 0.75 | CES2 (0.40) | DAORAB9AMEN1KMT2AMAPT | |
| SCHEMBL9564369 | 0.74 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL9564408 | 0.74 | ALDH1A1 (0.39) | L3MBTL1GAASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL9564366 | 0.71 | GAA (0.50) | GAASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL9564371 | 0.71 | GAA (0.50) | GAASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL9564393 | 0.71 | TP53 (0.35) | DAOL3MBTL1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL9564387 | 0.71 | TP53 (0.35) | DAOL3MBTL1SMN1; SMN2ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563686-A1 | Utilization of 3 substituted amino isoxazole derivatives against endoparasites, new 3 substituted amino isoxazols and process for their preparation | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |