Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10874394 | 0.78 | MAPT (0.48) | ALDH1A1KMT2ATDP1MEN1POLB | |
| SCHEMBL2960085 | 0.76 | ALDH1A1 (0.57) | ALDH1A1KMT2AOPRM1OPRD1MAPK1 | |
| SCHEMBL9564386 | 0.74 | DAO (0.41) | ALDH1A1KMT2AL3MBTL1MEN1GAA | |
| SCHEMBL9564371 | 0.72 | GAA (0.50) | ALDH1A1KMT2AMAPK1MEN1POLB | |
| SCHEMBL9564366 | 0.72 | GAA (0.50) | ALDH1A1KMT2AMAPK1MEN1POLB | |
| SCHEMBL2692103 | 0.71 | MAPT (0.52) | ALDH1A1KMT2AMAPK1MEN1GAA | |
| SCHEMBL9564388 | 0.71 | MAPT (0.52) | ALDH1A1KMT2AMAPK1MEN1GAA | |
| SCHEMBL2692097 | 0.71 | MAPT (0.52) | ALDH1A1KMT2AMAPK1MEN1GAA | |
| SCHEMBL9564362 | 0.68 | GSK3B (0.42) | KMT2AMAPK1L3MBTL1POLBGAA | |
| SCHEMBL7488352 | 0.68 | ALDH1A1 (0.54) | ALDH1A1KMT2AOPRM1OPRD1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563686-A1 | Utilization of 3 substituted amino isoxazole derivatives against endoparasites, new 3 substituted amino isoxazols and process for their preparation | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |