Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | GPR174 | Q9BXC1 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564489 | 0.92 | MEN1 (0.37) | MEN1KMT2AGPR174MAPTALDH1A1 | |
| SCHEMBL9564487 | 0.86 | MEN1 (0.43) | MEN1KMT2AALDH1A1LMNACYP1A2 | |
| SCHEMBL9564488 | 0.84 | MEN1 (0.38) | MEN1KMT2AGPR174MAPTALDH1A1 | |
| SCHEMBL9564473 | 0.83 | GPR174 (0.44) | KMT2AGPR174MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9564509 | 0.82 | MEN1 (0.38) | MEN1KMT2AGPR174MAPTALDH1A1 | |
| SCHEMBL9564507 | 0.81 | RXFP1 (0.40) | MEN1KMT2AGPR174MAPTALDH1A1 | |
| SCHEMBL9564502 | 0.79 | MEN1 (0.39) | MEN1KMT2AALDH1A1LMNAMAPK10 | |
| SCHEMBL9564459 | 0.78 | MEN1 (0.40) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL23037281 | 0.78 | TOP2A (0.47) | KMT2AALDH1A1TOP2ATOP2BUSP2 | |
| SCHEMBL9561861 | 0.75 | ADRB2 (0.43) | MEN1KMT2AALDH1A1TOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531958-A1 | 6-Aminoquinolones, their synthesis and their use as antibacterial agents | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1993-03-17 | — | — | EP | disclosed |