Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TTK | P33981 | 4/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564504 | 0.85 | RXFP1 (0.42) | RXFP1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9564473 | 0.83 | GPR174 (0.44) | ALDH1A1KMT2AMAPTGPR174 | |
| SCHEMBL9564489 | 0.81 | MEN1 (0.37) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL9564450 | 0.81 | MEN1 (0.40) | ALDH1A1MEN1KMT2AMAPTSIRT6 | |
| SCHEMBL9564491 | 0.75 | POLB (0.54) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL9564488 | 0.72 | MEN1 (0.38) | ALDH1A1MEN1KMT2AMAPTHTR2C | |
| SCHEMBL9564483 | 0.71 | PIK3CA (0.37) | ALDH1A1MEN1KMT2ATTK | |
| SCHEMBL9564469 | 0.71 | LGMN (0.41) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL9564506 | 0.71 | MAPT (0.38) | RXFP1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9564509 | 0.70 | MEN1 (0.38) | ALDH1A1MEN1KMT2AMAPTHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531958-A1 | 6-Aminoquinolones, their synthesis and their use as antibacterial agents | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1993-03-17 | — | — | EP | disclosed |