Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564450 | 0.92 | MEN1 (0.40) | MEN1KMT2ASIRT6MAPK10LMNA | |
| SCHEMBL9564502 | 0.85 | MEN1 (0.39) | MEN1KMT2AMAPK10LMNAALDH1A1 | |
| SCHEMBL9564473 | 0.84 | GPR174 (0.44) | KMT2ALMNASMN1; SMN2ALDH1A1GPR174 | |
| SCHEMBL9564507 | 0.81 | RXFP1 (0.40) | MEN1KMT2ASIRT6ALDH1A1GPR174 | |
| SCHEMBL9564487 | 0.80 | MEN1 (0.43) | MEN1KMT2AMAPK10LMNAALDH1A1 | |
| SCHEMBL9564488 | 0.80 | MEN1 (0.38) | MEN1KMT2AMAPK10LMNASMN1; SMN2 | |
| SCHEMBL9564509 | 0.78 | MEN1 (0.38) | MEN1KMT2AMAPK10LMNASMN1; SMN2 | |
| SCHEMBL9564491 | 0.75 | POLB (0.54) | MEN1KMT2ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9564459 | 0.73 | MEN1 (0.40) | MEN1KMT2AMAPK10LMNASMN1; SMN2 | |
| SCHEMBL9564469 | 0.72 | LGMN (0.41) | MEN1KMT2AMAPK10LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531958-A1 | 6-Aminoquinolones, their synthesis and their use as antibacterial agents | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1993-03-17 | — | — | EP | disclosed |