Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.39 |
| ▸ | GRK6 | P43250 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | EEF2K | O00418 | 1/20 | 0.36 |
| ▸ | TTK | P33981 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564483 | 0.86 | PIK3CA (0.37) | PIK3CAALDH1A1MEN1KMT2AEEF2K | |
| SCHEMBL9564507 | 0.85 | RXFP1 (0.40) | RXFP1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9564469 | 0.82 | LGMN (0.41) | GRK6ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9564487 | 0.80 | MEN1 (0.43) | GRK6ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9564459 | 0.72 | MEN1 (0.40) | GRK6ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9564473 | 0.71 | GPR174 (0.44) | ALDH1A1KMT2AMAPT | |
| SCHEMBL9564461 | 0.70 | AURKA (0.37) | ALDH1A1MEN1KMT2A | |
| SCHEMBL9564489 | 0.70 | MEN1 (0.37) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL9564450 | 0.69 | MEN1 (0.40) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9564509 | 0.67 | MEN1 (0.38) | ALDH1A1MEN1KMT2AMAPTHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531958-A1 | 6-Aminoquinolones, their synthesis and their use as antibacterial agents | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1993-03-17 | — | — | EP | disclosed |