Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 2/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TTK | P33981 | 1/20 | 0.35 |
| ▸ | GRK6 | P43250 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564467 | 0.85 | KDM4E (0.41) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL9564473 | 0.85 | GPR174 (0.44) | ALDH1A1KMT2AMAPTTP53GAA | |
| SCHEMBL9564502 | 0.82 | MEN1 (0.39) | ALDH1A1MEN1KMT2ALMNAGRK6 | |
| SCHEMBL9564487 | 0.82 | MEN1 (0.43) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL9564504 | 0.82 | RXFP1 (0.42) | KDM4EALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9564472 | 0.75 | KDM4E (0.42) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL9564459 | 0.74 | MEN1 (0.40) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL9564482 | 0.73 | KDM4E (0.38) | LGMNKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL9564465 | 0.72 | HSD17B10 (0.45) | KDM4EALDH1A1HSD17B10TP53GAA | |
| SCHEMBL9564489 | 0.72 | MEN1 (0.37) | KDM4EALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531958-A1 | 6-Aminoquinolones, their synthesis and their use as antibacterial agents | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1993-03-17 | — | — | EP | disclosed |