Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TOP2A | P11388 | 2/20 | 0.31 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | LGMN | Q99538 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564462 | 0.74 | KCNH2 (0.43) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL9564486 | 0.73 | SMPD3 (0.41) | — | |
| SCHEMBL14585956 | 0.69 | ALDH1A1 (0.48) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL30615686 | 0.69 | ALDH1A1 (0.61) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL1915366 | 0.69 | ALDH1A1 (0.61) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL17453757 | 0.67 | KDM4E (0.49) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL29742967 | 0.67 | TOP2A (0.49) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL10475103 | 0.67 | TOP2A (0.49) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL1876500 | 0.66 | TOP2A (0.37) | KDM4EALDH1A1TOP2ATOP2BMAPT | |
| Hydrochloric Acid SCHEMBL29744471 | 0.66 | TOP2A (0.48) | KDM4EALDH1A1TOP2ATOP2BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531958-A1 | 6-Aminoquinolones, their synthesis and their use as antibacterial agents | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1993-03-17 | — | — | EP | disclosed |