Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20286630 | 0.87 | KCNH2 (0.48) | KCNH2HRH3ALDH1A1LMNAKDM4E | |
| SCHEMBL9564486 | 0.77 | SMPD3 (0.41) | OPRM1 | |
| SCHEMBL9564484 | 0.74 | KDM4E (0.31) | ALDH1A1LMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL30615686 | 0.71 | ALDH1A1 (0.61) | ALDH1A1LMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL1915366 | 0.71 | ALDH1A1 (0.61) | ALDH1A1LMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL4589715 | 0.70 | BCL2A1 (0.44) | KCNH2HRH3ALDH1A1LMNAKDM4E | |
| SCHEMBL8114412 | 0.70 | BCL2A1 (0.44) | KCNH2HRH3ALDH1A1LMNAKDM4E | |
| SCHEMBL5569136 | 0.68 | ALDH1A1 (0.52) | ALDH1A1LMNAKDM4EPOLBBCL2A1 | |
| SCHEMBL5567965 | 0.68 | ALDH1A1 (0.52) | ALDH1A1LMNAKDM4EPOLBBCL2A1 | |
| SCHEMBL5567969 | 0.68 | ALDH1A1 (0.52) | ALDH1A1LMNAKDM4EPOLBBCL2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531958-A1 | 6-Aminoquinolones, their synthesis and their use as antibacterial agents | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1993-03-17 | — | — | EP | disclosed |