Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD3 | Q9NY59 | 11/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.38 |
| ▸ | SMPD2 | O60906 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564462 | 0.77 | KCNH2 (0.43) | OPRM1 | |
| SCHEMBL9564484 | 0.73 | KDM4E (0.31) | — | |
| SCHEMBL30564229 | 0.68 | ALDH1A1 (0.48) | — | |
| SCHEMBL3546557 | 0.68 | SMPD3 (0.49) | SMPD3MTNR1AMTNR1BAKT1 | |
| SCHEMBL5203906 | 0.67 | CASP6 (0.50) | SMPD3MTNR1AMTNR1BAKT1 | |
| SCHEMBL3551660 | 0.67 | CASP6 (0.50) | SMPD3MTNR1AMTNR1BAKT1 | |
| SCHEMBL3551801 | 0.67 | CASP6 (0.50) | SMPD3MTNR1AMTNR1BAKT1 | |
| SCHEMBL1876500 | 0.66 | TOP2A (0.37) | — | |
| Hydrochloric Acid SCHEMBL5406630 | 0.66 | FPR1 (0.49) | SMPD3MTNR1AMTNR1BAKT1 | |
| Hydrochloric Acid SCHEMBL5383077 | 0.66 | FPR1 (0.49) | SMPD3MTNR1AMTNR1BAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531958-A1 | 6-Aminoquinolones, their synthesis and their use as antibacterial agents | MEDIOLANUM FARMACEUTICI S.P.A. (IT) | 1993-03-17 | — | — | EP | disclosed |