Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8573320 | 0.83 | NPC1 (0.44) | SMN1; SMN2NPC1LMNARAB9AMEN1 | |
| SCHEMBL8572394 | 0.79 | NPC1 (0.41) | SMN1; SMN2NPC1LMNARAB9AKMT2A | |
| SCHEMBL8568489 | 0.79 | NPC1 (0.48) | SMN1; SMN2NPC1LMNARAB9AMEN1 | |
| SCHEMBL6761097 | 0.78 | ALDH1A1 (0.43) | SMN1; SMN2NPC1LMNARAB9AKMT2A | |
| SCHEMBL8566680 | 0.75 | NPSR1 (0.60) | SMN1; SMN2NPC1LMNARAB9AMEN1 | |
| SCHEMBL8565123 | 0.73 | ALDH1A1 (0.49) | SMN1; SMN2NPC1LMNARAB9AMEN1 | |
| SCHEMBL8568524 | 0.72 | TSHR (0.43) | SMN1; SMN2NPC1LMNARAB9AALDH1A1 | |
| SCHEMBL8353825 | 0.71 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1LMNARAB9AMEN1 | |
| SCHEMBL8358005 | 0.71 | HTT (0.49) | SMN1; SMN2NPC1LMNARAB9AALDH1A1 | |
| SCHEMBL8569581 | 0.71 | ALDH1A1 (0.44) | SMN1; SMN2NPC1LMNARAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536900-A2 | Process for preparing 1,2,4-Thiadiazole Derivatives | KATAYAMA SEIYAKUSYO CO. Ltd. (JP) | 1993-04-14 | — | — | EP | disclosed |