Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.54 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.54 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.54 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | EIF4E | P06730 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564533 | 0.79 | GRIA1 (0.58) | GRIA1GRIA2GRIA3GRIA4CA2 | |
| SCHEMBL9564548 | 0.74 | GRIA1 (0.70) | GRIA1GRIA2GRIA3GRIA4CA2 | |
| SCHEMBL9564541 | 0.74 | GRIA1 (0.63) | GRIA1GRIA2GRIA3GRIA4CA2 | |
| SCHEMBL9564526 | 0.74 | GRIA1 (0.66) | GRIA1GRIA2GRIA3GRIA4CA2 | |
| SCHEMBL9564531 | 0.74 | GRIA1 (0.66) | GRIA1GRIA2GRIA3GRIA4CA2 | |
| SCHEMBL9564528 | 0.74 | GRIA1 (0.56) | GRIA1GRIA2GRIA3GRIA4CA2 | |
| SCHEMBL9564538 | 0.73 | GRIA1 (0.58) | GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL9564532 | 0.70 | GRIA1 (1.00) | GRIA1GRIA2GRIA3GRIA4L3MBTL1 | |
| SCHEMBL13850474 | 0.68 | CA2 (0.51) | CA2AKR1B1L3MBTL1KDM4EKMT2A | |
| SCHEMBL9564547 | 0.68 | GRIA1 (0.58) | GRIA1GRIA2GRIA3GRIA4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542609-A1 | 3-sulfonylamino-2-(1H)-quinolinones and 7-aza derivatives as excitatory amino acids antagonists | ADIR ET COMPAGNIE (FR) | 1993-05-19 | — | — | EP | disclosed |