Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 12/20 | 0.36 |
| ▸ | ATF1 | P18846 | 10/20 | 0.36 |
| ▸ | XPO1 | O14980 | 4/20 | 0.33 |
| ▸ | STK17B | O94768 | 1/20 | 0.33 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.33 |
| ▸ | JUN | P05412 | 3/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.33 |
| ▸ | RELA | Q04206 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2481483 | 0.84 | NFKB1 (0.46) | NFKB1ATF1XPO1JUNNFKB2 | |
| SCHEMBL9626746 | 0.78 | NFKB1 (0.41) | NFKB1ATF1XPO1STK17BSTK17A | |
| SCHEMBL7087131 | 0.78 | NFKB1 (0.37) | NFKB1ATF1XPO1JUNNFKB2 | |
| SCHEMBL22576229 | 0.78 | ALDH1A1 (0.49) | NFKB1ATF1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL31456731 | 0.75 | KDM4E (0.35) | NFKB1ATF1STK17BSTK17AKDM4E | |
| SCHEMBL9564872 | 0.74 | MEN1 (0.49) | KDM4ESMN1; SMN2GAA | |
| SCHEMBL27471255 | 0.73 | NFKB1 (0.46) | NFKB1ATF1XPO1JUNNFKB2 | |
| SCHEMBL31456685 | 0.72 | LRRK2 (0.34) | NFKB1ATF1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3129046 | 0.71 | XPO1 (0.48) | NFKB1ATF1XPO1JUNNFKB2 | |
| SCHEMBL31053755 | 0.70 | S100A9 (0.36) | NFKB1ATF1XPO1STK17BSTK17A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569912-A1 | 4-alkyl-substituted pyrimidine-5-carboxanilides, process for their preparation, compositions containing them and their use as fungicides | Hoechst Schering AgrEvo GmbH (DE) | 1993-11-18 | — | — | EP | disclosed |