Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564940 | 0.82 | NFKB1 (0.43) | MEN1KMT2AMAPTHTTSMN1; SMN2 | |
| SCHEMBL9564847 | 0.74 | NFKB1 (0.36) | SMN1; SMN2KDM4EGAA | |
| SCHEMBL6628806 | 0.71 | PDK1 (0.56) | MEN1KMT2AMAPTHTTATM | |
| SCHEMBL9564908 | 0.71 | NFKB1 (0.63) | — | |
| SCHEMBL9564867 | 0.70 | ATF1 (0.48) | MEN1KMT2AMAPTHTTL3MBTL1 | |
| SCHEMBL2095473 | 0.70 | HPGD (0.58) | MEN1KMT2AMAPTATMPDK1 | |
| SCHEMBL11184124 | 0.67 | NPC1 (0.63) | MEN1KMT2AMAPTHTTPOLB | |
| SCHEMBL2854533 | 0.67 | MEN1 (0.46) | MEN1KMT2AMAPTPDK1PDK2 | |
| SCHEMBL31718129 | 0.66 | PDK1 (0.69) | MEN1KMT2AMAPTHTTATM | |
| SCHEMBL14254880 | 0.66 | PDK1 (0.69) | MEN1KMT2AMAPTHTTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569912-A1 | 4-alkyl-substituted pyrimidine-5-carboxanilides, process for their preparation, compositions containing them and their use as fungicides | Hoechst Schering AgrEvo GmbH (DE) | 1993-11-18 | — | — | EP | disclosed |