Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 8/20 | 0.63 |
| ▸ | ACHE | P22303 | 3/20 | 0.51 |
| ▸ | BACE1 | P56817 | 3/20 | 0.51 |
| ▸ | BCHE | P06276 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MLNR | O43193 | 1/20 | 0.46 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.46 |
| ▸ | EED | O75530 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564952 | 0.83 | SSTR5 (0.69) | SSTR5ACHEBACE1BCHEKCNH2 | |
| SCHEMBL9564890 | 0.82 | ALDH1A1 (0.46) | SSTR5ACHEBACE1BCHESLC6A4 | |
| SCHEMBL9564786 | 0.80 | ALDH1A1 (0.47) | GAALMNAMAPTHTTKMT2A | |
| SCHEMBL9564924 | 0.77 | KCNH2 (0.47) | SSTR5KCNH2NR4A2SIGMAR1GAA | |
| SCHEMBL11573432 | 0.77 | SSTR5 (0.74) | SSTR5ACHEBACE1BCHEKCNH2 | |
| SCHEMBL9564765 | 0.74 | KCNH2 (0.58) | SSTR5ACHEBACE1KCNH2NR4A2 | |
| SCHEMBL9564827 | 0.74 | SSTR5 (0.44) | SSTR5KCNH2NR4A2SIGMAR1GAA | |
| SCHEMBL12046435 | 0.74 | SSTR5 (0.64) | SSTR5ACHEBACE1BCHEKCNH2 | |
| Bromide SCHEMBL9564852 | 0.73 | KCNH2 (0.57) | SSTR5KCNH2NR4A2SIGMAR1GAA | |
| SCHEMBL3997031 | 0.71 | ACHE (0.68) | SSTR5ACHEBACE1BCHESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258380-A | Antiallergens, antihistamines | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-11-02 | — | — | US | disclosed |
| US-5041448-A | Antiallergens | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-08-20 | — | — | US | disclosed |
| EP-0206415-A2 | (4-Piperidinylmethyl and -hetero)purines | JANSSEN PHARMACEUTICA N.V. (BE) | 1986-12-30 | — | — | EP | disclosed |