Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.45 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564964 | 0.84 | ALDH1A1 (0.46) | ALDH1A1CCR3SSTR5SLC6A4SLC6A3 | |
| SCHEMBL9564865 | 0.82 | SSTR5 (0.63) | SSTR5SLC6A4SLC6A3BCHEACHE | |
| SCHEMBL9536547 | 0.81 | SSTR5 (0.52) | ALDH1A1CCR3SSTR5SLC6A4SLC6A3 | |
| SCHEMBL9564937 | 0.80 | HSD17B10 (0.47) | ALDH1A1TSHR | |
| SCHEMBL9866073 | 0.78 | CCR3 (0.44) | ALDH1A1CCR3SSTR5SLC6A4SLC6A3 | |
| SCHEMBL9536543 | 0.77 | SSTR5 (0.66) | ALDH1A1SSTR5SLC6A3TSHR | |
| SCHEMBL9564956 | 0.77 | CYP1A2 (0.54) | ALDH1A1CCR3SSTR5TSHR | |
| SCHEMBL9535367 | 0.76 | SLC6A9 (0.58) | CCR3SSTR5 | |
| SCHEMBL9564830 | 0.76 | SSTR5 (0.43) | CCR3SSTR5ACHEBACE1 | |
| SCHEMBL9565004 | 0.73 | HTR1A (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258380-A | Antiallergens, antihistamines | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-11-02 | — | — | US | disclosed |
| US-5041448-A | Antiallergens | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-08-20 | — | — | US | disclosed |
| EP-0206415-A2 | (4-Piperidinylmethyl and -hetero)purines | JANSSEN PHARMACEUTICA N.V. (BE) | 1986-12-30 | — | — | EP | disclosed |