Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.42 |
| ▸ | ACE | P12821 | 5/20 | 0.40 |
| ▸ | FCER2 | P06734 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 4/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.37 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.37 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11400555 | 0.86 | CTSS (0.36) | ACEMDM4MDM2CTSSCTSK | |
| SCHEMBL2583065 | 0.86 | CTSS (0.46) | RENACEHPGDSMDM4MDM2 | |
| SCHEMBL2583067 | 0.86 | CTSS (0.46) | RENACEHPGDSMDM4MDM2 | |
| SCHEMBL9564881 | 0.86 | FCER2 (0.42) | ACEFCER2HPGDSF10 | |
| SCHEMBL9564935 | 0.82 | ACE (0.43) | ACECTSSCTSKCTSLCTSB | |
| SCHEMBL9564882 | 0.82 | HPGDS (0.46) | ACEFCER2HPGDS | |
| SCHEMBL2585648 | 0.77 | MDM4 (0.55) | MDM4MDM2CTSSCTSKERAP2 | |
| SCHEMBL2585645 | 0.77 | MDM4 (0.55) | MDM4MDM2CTSSCTSKERAP2 | |
| SCHEMBL2583010 | 0.76 | TACR1 (0.51) | ACE | |
| SCHEMBL2583014 | 0.76 | TACR1 (0.51) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0565148-A2 | Intermediates for preparation of H-Arg-X-Y-Z-Tyr-R | ORTHO PHARMACEUTICAL CORPORATION (US) | 1993-10-13 | — | — | EP | disclosed |
| EP-0042291-B1 | METHODS AND COMPOSITIONS FOR PREPARATION OF H-ARG-X-Z-Y-TYR-R | ORTHO PHARMACEUTICAL CORPORATION (US) | 1986-12-10 | — | — | EP | disclosed |
| US-4369137-A | N-Protected pentapeptides useful as intermediates in the preparation of thymopoietin pentapeptide | ORTHO PHARMACEUTICAL CORPORATION (US) | 1983-01-18 | — | — | US | disclosed |
| EP-0042291-A2 | Methods and compositions for preparation of H-Arg-X-Z-Y-Tyr-R | ORTHO PHARMACEUTICAL CORPORATION (US) | 1981-12-23 | — | — | EP | disclosed |
| US-4298523-A | OLIGOPEPTIDES OF ARGININE, LYSINE, VALINE, SARCOSINE, ASPARTIC OR GLUTAMIC ACID, AND TYROSINE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1981-11-03 | — | — | US | disclosed |