Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 4/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | CASP9 | P55211 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.43 |
| ▸ | CCKBR | P32239 | 3/20 | 0.43 |
| ▸ | CCKAR | P32238 | 3/20 | 0.43 |
| ▸ | REN | P00797 | 4/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11399274 | 0.92 | CTSD (0.43) | CTSDCASP3CASP1CASP9CASP7 | |
| SCHEMBL8612027 | 0.83 | CTSS (0.54) | CTSDCASP3CASP1CASP9CASP7 | |
| SCHEMBL7275592 | 0.81 | GNPAT (0.58) | CASP3CASP1CASP9CASP7CTSL | |
| SCHEMBL9555165 | 0.80 | CASP3 (0.50) | CASP3CASP1CASP9CASP7REN | |
| SCHEMBL29770301 | 0.80 | CTSS (0.60) | CTSDCASP3CASP1CASP7CTSL | |
| SCHEMBL8137308 | 0.80 | MEN1 (0.55) | CTSDCTSLRENCTSSCTSK | |
| SCHEMBL9411663 | 0.79 | KLK5 (0.52) | CTSDCTSSCTSK | |
| SCHEMBL3937813 | 0.78 | PPARA (0.56) | CTSSCTSK | |
| SCHEMBL29396254 | 0.78 | PPARA (0.56) | CTSSCTSK | |
| SCHEMBL7235877 | 0.78 | CTSS (0.63) | CTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0565148-A2 | Intermediates for preparation of H-Arg-X-Y-Z-Tyr-R | ORTHO PHARMACEUTICAL CORPORATION (US) | 1993-10-13 | — | — | EP | disclosed |
| US-4369137-A | N-Protected pentapeptides useful as intermediates in the preparation of thymopoietin pentapeptide | ORTHO PHARMACEUTICAL CORPORATION (US) | 1983-01-18 | — | — | US | disclosed |
| EP-0042291-A2 | Methods and compositions for preparation of H-Arg-X-Z-Y-Tyr-R | ORTHO PHARMACEUTICAL CORPORATION (US) | 1981-12-23 | — | — | EP | disclosed |
| US-4298523-A | OLIGOPEPTIDES OF ARGININE, LYSINE, VALINE, SARCOSINE, ASPARTIC OR GLUTAMIC ACID, AND TYROSINE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1981-11-03 | — | — | US | disclosed |