Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.42 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7433203 | 0.83 | PLOD2 (0.51) | PLOD2HDAC1HDAC8THRBPLOD3 | |
| SCHEMBL7443990 | 0.77 | PLOD2 (0.57) | PLOD2THRBPLOD3PLOD1ALDH1A1 | |
| SCHEMBL7439167 | 0.77 | PLOD2 (0.50) | PLOD2HDAC1HDAC8THRBPLOD3 | |
| SCHEMBL7436954 | 0.74 | PLOD2 (0.53) | PLOD2HDAC1HDAC8THRBPLOD3 | |
| SCHEMBL27374976 | 0.73 | PLOD2 (0.49) | PLOD2HDAC1HDAC8THRBPLOD3 | |
| SCHEMBL7327368 | 0.73 | HDAC1 (0.57) | PLOD2HDAC1HDAC8THRBALDH1A1 | |
| SCHEMBL16404277 | 0.73 | PLOD2 (0.51) | PLOD2HDAC1HDAC8THRBPLOD3 | |
| SCHEMBL15973481 | 0.72 | PLOD2 (0.67) | PLOD2HDAC1HDAC8THRBPLOD3 | |
| SCHEMBL5113226 | 0.72 | ALDH1A1 (0.52) | PLOD2THRBPLOD3PLOD1ALDH1A1 | |
| SCHEMBL23014378 | 0.72 | PLOD2 (0.57) | PLOD2HDAC1HDAC8THRBPLOD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543245-A1 | Renin inhibiting amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1993-05-26 | — | — | EP | disclosed |