Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 12/20 | 0.52 |
| ▸ | CA9 | Q16790 | 11/20 | 0.52 |
| ▸ | CA1 | P00915 | 11/20 | 0.52 |
| ▸ | CA12 | O43570 | 10/20 | 0.52 |
| ▸ | CA7 | P43166 | 4/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11555539 | 0.78 | MAPT (0.61) | LMNASMN1; SMN2KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL2962006 | 0.78 | HSD11B1 (0.57) | LMNASMN1; SMN2KDM4EALDH1A1HSD11B1 | |
| SCHEMBL19212308 | 0.77 | ADRB1 (0.59) | LMNAKDM4EALDH1A1 | |
| SCHEMBL6442002 | 0.76 | DRD4 (0.66) | ALDH1A1CA2CA9CA1CA12 | |
| SCHEMBL9097181 | 0.76 | LMNA (0.70) | LMNASMN1; SMN2KDM4EALDH1A1CA2 | |
| SCHEMBL18118187 | 0.76 | LMNA (0.70) | LMNASMN1; SMN2KDM4EALDH1A1CA2 | |
| SCHEMBL28396664 | 0.75 | ADRB1 (0.71) | LMNAKDM4EALDH1A1 | |
| SCHEMBL5722125 | 0.75 | ALDH1A1 (0.64) | LMNAKDM4EALDH1A1CA2CA9 | |
| SCHEMBL18118191 | 0.74 | LMNA (0.68) | LMNASMN1; SMN2KDM4EALDH1A1CA2 | |
| SCHEMBL8193969 | 0.74 | LMNA (0.68) | LMNASMN1; SMN2KDM4EALDH1A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548798-A1 | Antiviral agent | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |