SCHEMBL9566069

SCHEMBL9566069

CON(C)C(=O)NN=C(c1ccc(Cl)cc1)c1ccc(OS(C)(=O)=O)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.45
PKM P14618 1/20 0.45
ALDH1A1 P00352 3/20 0.38
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
MAPT P10636 2/20 0.37
HPGD P15428 1/20 0.37
KDM4E B2RXH2 1/20 0.37
GAA P10253 1/20 0.37
CYP11B1 P15538 1/20 0.37
CYP11B2 P19099 1/20 0.37
NFE2L2 Q16236 1/20 0.36
ENPP3 O14638 3/20 0.36
ENPP1 P22413 3/20 0.36
HTT P42858 1/20 0.36
ENPP2 Q13822 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
NPC1 O15118 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9416661 0.88 RAB9A (0.42) RAB9APKMALDH1A1MAOAMAOB
SCHEMBL11176240 0.83 MAPT (0.49) RAB9AALDH1A1MAOAMAOBMEN1
SCHEMBL11183016 0.81 FAAH (0.42) ALDH1A1MEN1KMT2AMAPTHPGD
SCHEMBL11098937 0.80 MEN1 (0.44) RAB9AALDH1A1MEN1KMT2AMAPT
SCHEMBL11183078 0.80 PPARA (0.44) ALDH1A1MEN1KMT2AMAPTKDM4E
SCHEMBL9566079 0.79 NFE2L2 (0.38) RAB9APKMALDH1A1MAOAMAOB
SCHEMBL11171501 0.79 ENPP1 (0.53) RAB9AALDH1A1MAOAMAOBMEN1
SCHEMBL11187189 0.79 POLB (0.53) RAB9AALDH1A1MAOAMAOBMEN1
SCHEMBL10974595 0.79 ALDH1A1 (0.45) ALDH1A1MEN1KMT2AMAPTHPGD
SCHEMBL14359275 0.78 SMN1; SMN2 (0.47) PKMALDH1A1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0566534-A1 Derivatives of benzophenone CIBA-GEIGY AG (CH) 1993-10-20 EP claimed
EP-0566534-A1 Derivatives of benzophenone CIBA-GEIGY AG (CH) 1993-10-20 EP disclosed