Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566100 | 0.87 | ALDH1A1 (0.35) | NFE2L2ALDH1A1CYP11B1CYP11B2HPGD | |
| SCHEMBL10969828 | 0.83 | CA1 (0.41) | NFE2L2ALDH1A1CYP11B1CYP11B2HPGD | |
| SCHEMBL9566069 | 0.79 | RAB9A (0.45) | NFE2L2ALDH1A1CYP11B1CYP11B2HPGD | |
| SCHEMBL29386050 | 0.79 | STS (0.38) | NFE2L2ALDH1A1CYP11B1CYP11B2HPGD | |
| SCHEMBL15138714 | 0.79 | STS (0.38) | NFE2L2ALDH1A1CYP11B1CYP11B2HPGD | |
| SCHEMBL15129863 | 0.79 | STS (0.38) | NFE2L2ALDH1A1CYP11B1CYP11B2HPGD | |
| SCHEMBL9566152 | 0.76 | PAX8 (0.36) | ALDH1A1RAB9AMEN1KMT2AMAOB | |
| SCHEMBL9565958 | 0.76 | DRD2 (0.35) | ALDH1A1CYP11B1CYP11B2CA1CA2 | |
| SCHEMBL9565985 | 0.75 | CYP11B1 (0.34) | NFE2L2ALDH1A1CYP11B1CYP11B2HPGD | |
| SCHEMBL9566056 | 0.74 | CYP11B1 (0.34) | NFE2L2ALDH1A1CYP11B1CYP11B2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566534-A1 | Derivatives of benzophenone | CIBA-GEIGY AG (CH) | 1993-10-20 | — | — | EP | claimed |
| EP-0566534-A1 | Derivatives of benzophenone | CIBA-GEIGY AG (CH) | 1993-10-20 | — | — | EP | disclosed |