Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL125550 | 0.84 | RAB9A (0.52) | RAB9AALDH1A1TDP1HSP90AA1HPGD | |
| SCHEMBL9566572 | 0.81 | HTR2B (0.68) | RAB9AALDH1A1HSP90AA1AGPAT2SMN1; SMN2 | |
| SCHEMBL5069137 | 0.81 | NPC1 (0.68) | RAB9AALDH1A1TDP1HSP90AA1HPGD | |
| SCHEMBL9566466 | 0.81 | HTR2B (0.68) | RAB9AHSP90AA1SMN1; SMN2NPC1HTR2B | |
| SCHEMBL22207162 | 0.80 | RAB9A (0.47) | RAB9AALDH1A1TDP1HSP90AA1HPGD | |
| SCHEMBL18216909 | 0.79 | L3MBTL1 (0.40) | RAB9AALDH1A1TDP1HPGDSMN1; SMN2 | |
| SCHEMBL26232916 | 0.79 | ALDH1A1 (0.39) | RAB9AALDH1A1TDP1HPGDSMN1; SMN2 | |
| SCHEMBL26232922 | 0.79 | KMT2A (0.44) | RAB9AALDH1A1TDP1HPGDSMN1; SMN2 | |
| SCHEMBL4371820 | 0.77 | AGPAT2 (0.76) | RAB9AALDH1A1AGPAT2SMN1; SMN2KDM4E | |
| SCHEMBL17094717 | 0.76 | TDP1 (0.40) | RAB9AALDH1A1TDP1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563386-A1 | ANTICANCER COMPOSITION AND COMPOUND | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-10-06 | — | — | EP | disclosed |