Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | CES2 | O00748 | 2/20 | 0.31 |
| ▸ | CES1 | P23141 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ASPH | Q12797 | 1/20 | 0.31 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566709 | 0.89 | LMNA (0.35) | KEAP1NFE2L2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL9566700 | 0.88 | KEAP1 (0.33) | KEAP1NFE2L2MAPT | |
| SCHEMBL7813771 | 0.85 | KEAP1 (0.37) | KEAP1NFE2L2MAPTCES2CES1 | |
| SCHEMBL9566656 | 0.82 | KEAP1 (0.34) | KEAP1NFE2L2MAPT | |
| SCHEMBL8595294 | 0.79 | MAPT (0.35) | KEAP1NFE2L2MAPTCES2CES1 | |
| SCHEMBL9566702 | 0.79 | MAPT (0.35) | KEAP1NFE2L2MAPTCES2CES1 | |
| SCHEMBL9566689 | 0.78 | KEAP1 (0.33) | KEAP1NFE2L2MAPT | |
| SCHEMBL9566673 | 0.78 | KEAP1 (0.36) | KEAP1NFE2L2MAPT | |
| SCHEMBL7804048 | 0.78 | KEAP1 (0.37) | KEAP1NFE2L2ALDH1A1TSHRMAPT | |
| SCHEMBL9566698 | 0.77 | KEAP1 (0.32) | KEAP1NFE2L2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545866-A1 | Process for the preparation of trifluorobenzol derivatives | CIBA-GEIGY AG (CH) | 1993-06-09 | — | — | EP | disclosed |