Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566862 | 0.89 | ABL1 (0.51) | ABL1HTTKMT2ASMN1; SMN2P4HTM | |
| SCHEMBL9566768 | 0.88 | P4HTM (0.46) | ABL1HTTKMT2ASMN1; SMN2P4HTM | |
| SCHEMBL9566771 | 0.86 | P4HTM (0.44) | HTTKMT2ASMN1; SMN2P4HTMHIF1A | |
| SCHEMBL9566780 | 0.86 | KMT2A (0.45) | HTTKMT2ASMN1; SMN2P4HTMHIF1A | |
| SCHEMBL9566765 | 0.86 | P4HTM (0.49) | ABL1HTTKMT2ASMN1; SMN2P4HTM | |
| SCHEMBL9566855 | 0.84 | RAB9A (0.50) | HTTKMT2ASMN1; SMN2P4HTMLMNA | |
| SCHEMBL9566747 | 0.83 | P4HTM (0.44) | HTTKMT2ASMN1; SMN2P4HTMHIF1A | |
| SCHEMBL9519377 | 0.83 | P4HTM (0.45) | P4HTM | |
| SCHEMBL9566887 | 0.80 | P4HTM (0.69) | KMT2ASMN1; SMN2P4HTMLMNAKDM4E | |
| SCHEMBL9566803 | 0.78 | P4HTM (0.66) | KMT2ASMN1; SMN2P4HTMLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |