Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.45 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566871 | 0.90 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9566765 | 0.87 | P4HTM (0.49) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9566768 | 0.85 | P4HTM (0.46) | RAB9ANPC1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL9566832 | 0.84 | ABL1 (0.48) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9566780 | 0.83 | KMT2A (0.45) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9566771 | 0.83 | P4HTM (0.44) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9566861 | 0.83 | P4HTM (0.61) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9566756 | 0.82 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9566738 | 0.82 | CXCR2 (0.64) | RAB9ANPC1KMT2AMEN1RXFP1 | |
| SCHEMBL9566829 | 0.81 | CXCR2 (0.58) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |