Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367679 | 0.95 | HPGD (0.44) | HPGDMEN1KMT2AALDH1A1POLB | |
| SCHEMBL9706102 | 0.93 | LOXL2 (0.46) | HPGDGAA | |
| SCHEMBL9706016 | 0.90 | ALDH1A1 (0.43) | HPGDMEN1KMT2AALDH1A1GAA | |
| SCHEMBL8782005 | 0.89 | ALDH1A1 (0.43) | HPGDMEN1KMT2AALDH1A1GAA | |
| SCHEMBL9572913 | 0.89 | ALDH1A1 (0.43) | HPGDMEN1KMT2AALDH1A1GAA | |
| SCHEMBL9572972 | 0.88 | LOXL2 (0.46) | HPGD | |
| SCHEMBL9354128 | 0.86 | LOXL2 (0.48) | HPGD | |
| SCHEMBL9706023 | 0.82 | LOXL2 (0.46) | HPGD | |
| SCHEMBL9566818 | 0.81 | ALDH1A1 (0.44) | HPGDMEN1KMT2AALDH1A1GAA | |
| SCHEMBL8781962 | 0.81 | LOXL2 (0.47) | HPGDALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0479177-A2 | 4- or 5-substituted pyridine-2-carboxylic acids, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-04-08 | — | — | EP | disclosed |