Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566832 | 0.89 | ABL1 (0.48) | ABL1KMT2ATRPV1HTTSMN1; SMN2 | |
| SCHEMBL9566891 | 0.87 | P4HTM (0.49) | KMT2AHTTSMN1; SMN2HIF1AEPAS1 | |
| SCHEMBL9566787 | 0.85 | P4HTM (0.53) | KMT2AHTTSMN1; SMN2HIF1AEPAS1 | |
| SCHEMBL9566793 | 0.85 | KMT2A (0.48) | KMT2AHTTSMN1; SMN2HIF1AEPAS1 | |
| SCHEMBL9566814 | 0.85 | P4HTM (0.47) | KMT2AHTTSMN1; SMN2HIF1AEPAS1 | |
| SCHEMBL9566887 | 0.84 | P4HTM (0.69) | KMT2ASMN1; SMN2P4HTMMEN1LMNA | |
| SCHEMBL9566871 | 0.82 | RAB9A (0.53) | KMT2ASMN1; SMN2P4HTMMEN1LMNA | |
| SCHEMBL9566803 | 0.82 | P4HTM (0.66) | KMT2ASMN1; SMN2P4HTMMEN1LMNA | |
| SCHEMBL9566844 | 0.82 | SMN1; SMN2 (0.47) | KMT2AHTTSMN1; SMN2HIF1AEPAS1 | |
| SCHEMBL9566852 | 0.81 | P4HTM (0.55) | KMT2AP4HTMMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |