Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.52 |
| ▸ | NEK2 | P51955 | 1/20 | 0.52 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.52 |
| ▸ | EP300 | Q09472 | 1/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.45 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.45 |
| ▸ | EDNRA | P25101 | 9/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29643330 | 1.00 | CA2 (0.53) | CA2CHEK1NEK2LIMK1DYRK1A | |
| SCHEMBL2949640 | 0.86 | CHEK1 (0.57) | CA2CHEK1NEK2LIMK1DYRK1A | |
| SCHEMBL8720110 | 0.85 | CHEK1 (0.65) | CA2CHEK1NEK2LIMK1DYRK1A | |
| SCHEMBL1489217 | 0.77 | PARP1 (0.54) | DYRK1ACYP1A2TDP1GAAKMT2A | |
| SCHEMBL29375428 | 0.77 | PARP1 (0.54) | DYRK1ACYP1A2TDP1GAAKMT2A | |
| SCHEMBL23043531 | 0.77 | PARP1 (0.36) | CA2EDNRAGAAKMT2APARP1 | |
| SCHEMBL29914152 | 0.77 | PARP1 (0.36) | CA2EDNRAGAAKMT2APARP1 | |
| SCHEMBL27048034 | 0.77 | CA2 (0.37) | CA2CHEK1NEK2LIMK1DYRK1A | |
| SCHEMBL9566860 | 0.76 | MAPT (0.46) | CA2CHEK1NEK2LIMK1DYRK1A | |
| SCHEMBL545805 | 0.75 | ALDH1A1 (0.44) | CA2CHEK1NEK2LIMK1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3357928-B1 | NOVEL DYES WITH PHOSPHINIC ACID, PHOSPHINATE, PHOSPHONATE AND PHOSPHONAMIDATE SUBSTITUENTS AS AUXOCHROMIC GROUPS AND METHODS FOR PREPARING THE SAME | MAX PLANCK GESELLSCHAFT (DE) | 2021-01-06 | — | — | EP | disclosed |
| EP-3357928-B1 | NOVEL DYES WITH PHOSPHINIC ACID, PHOSPHINATE, PHOSPHONATE AND PHOSPHONAMIDATE SUBSTITUENTS AS AUXOCHROMIC GROUPS AND METHODS FOR PREPARING THE SAME | MAX PLANCK GESELLSCHAFT (DE) | 2021-01-06 | — | — | EP | disclosed |
| US-10174202-B2 | Dyes with phosphinic acid, phosphinate, phosphonate and phosphonamidate substituents as auxochromic groups and methods for preparing the same | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E. V. (DE) | 2019-01-08 | — | — | US | disclosed |
| US-10174202-B2 | Dyes with phosphinic acid, phosphinate, phosphonate and phosphonamidate substituents as auxochromic groups and methods for preparing the same | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E. V. (DE) | 2019-01-08 | — | — | US | disclosed |
| US-20180223102-A1 | NOVEL DYES WITH PHOSPHINIC ACID, PHOSPHINATE, PHOSPHONATE AND PHOSPHONAMIDATE SUBSTITUENTS AS AUXOCHROMIC GROUPS AND METHODS FOR PREPARING THE SAME | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E. V. (DE) | 2018-08-09 | — | — | US | disclosed |
| US-20180223102-A1 | NOVEL DYES WITH PHOSPHINIC ACID, PHOSPHINATE, PHOSPHONATE AND PHOSPHONAMIDATE SUBSTITUENTS AS AUXOCHROMIC GROUPS AND METHODS FOR PREPARING THE SAME | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E. V. (DE) | 2018-08-09 | — | — | US | disclosed |
| EP-3357928-A1 | NOVEL DYES WITH PHOSPHINIC ACID, PHOSPHINATE, PHOSPHONATE AND PHOSPHONAMIDATE SUBSTITUENTS AS AUXOCHROMIC GROUPS AND METHODS FOR PREPARING THE SAME | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2018-08-08 | — | — | EP | disclosed |
| EP-3357928-A1 | NOVEL DYES WITH PHOSPHINIC ACID, PHOSPHINATE, PHOSPHONATE AND PHOSPHONAMIDATE SUBSTITUENTS AS AUXOCHROMIC GROUPS AND METHODS FOR PREPARING THE SAME | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2018-08-08 | — | — | EP | disclosed |
| US-7767817-B2 | Water soluble boronic acid fluorescent reporter compounds and methods of use thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-08-03 | — | — | US | disclosed |
| US-20070274922-A1 | Water Soluble Boronic Acid Fluorescent Reporter Compounds and Methods of Use Thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-11-29 | — | — | US | disclosed |
| WO-2005024416-A1 | WATER SOLUBLE BORONIC ACID FLUORESCENT REPORTER COMPOUNDS AND METHODS OF USE THEREOF | WANG BINGHE (US) | 2005-03-17 | — | — | WO | disclosed |
| US-4045458-A | FRIEDEL-CRAFTS CATALYSTS | KANZAKI PAPER MANUFACTURING CO., LTD. (JA) | 1977-08-30 | — | — | US | disclosed |
| US-3930671-A | Color former and pressure-sensitive copying paper | FUJI PHOTO FILM CO., LTD. (JA) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070274922-A1 | Water Soluble Boronic Acid Fluorescent Reporter Compounds and Methods of Use Thereof | GUSB, BLVRB, BCL6 | CA2 956/4885CHEK1 3082/4885NEK2 2822/4885 |
| US-10174202-B2 | Dyes with phosphinic acid, phosphinate, phosphonate and phosphonamidate substituents as auxochromic groups and methods for preparing the same | OXSR1, RER1, CBR3 | CA2 696/4885CHEK1 2196/4885NEK2 3941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.