Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9311173 | 0.89 | PARP1 (0.45) | POLBKMT2AMEN1MAPTPARP1 | |
| SCHEMBL9566907 | 0.80 | AR (0.41) | POLBKMT2AMEN1MAPTPARP1 | |
| SCHEMBL27532886 | 0.77 | KIF11 (0.50) | MAPTPARP1TSHRCYP2C9KIF11 | |
| SCHEMBL9309057 | 0.74 | PARP1 (0.48) | KMT2AMEN1PARP1KIF11 | |
| SCHEMBL27409224 | 0.74 | KIF11 (0.44) | POLBKMT2AMEN1MAPTTSHR | |
| SCHEMBL132216 | 0.74 | TSHR (0.67) | POLBKMT2AMEN1MAPTMAOB | |
| SCHEMBL29385659 | 0.74 | TSHR (0.67) | POLBKMT2AMEN1MAPTMAOB | |
| SCHEMBL27410225 | 0.73 | DAO (0.49) | MAPTPARP1TSHRCYP2C9KIF11 | |
| SCHEMBL27413780 | 0.71 | KIF11 (0.46) | POLBMAPTTSHRCYP2C9KIF11 | |
| SCHEMBL17505145 | 0.71 | ALDH1A1 (0.57) | POLBKMT2AMEN1MAPTPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561252-A1 | 2-Oxoquinoline derivatives as angiotensin II antagonists | MERCK PATENT GmbH (DE) | 1993-09-22 | — | — | EP | disclosed |