Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9311173 | 0.82 | PARP1 (0.45) | KIF11RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL9566880 | 0.80 | MAP2K1 (0.44) | KIF11RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL9566894 | 0.80 | KIF11 (0.43) | ARKIF11RAB9AMAPTPTGES | |
| SCHEMBL9566941 | 0.79 | KIF11 (0.42) | KIF11RAB9AKMT2AMEN1POLB | |
| SCHEMBL9566925 | 0.77 | PDE3B (0.45) | KIF11RAB9AMAPTCYP2C9ALDH1A1 | |
| SCHEMBL27532886 | 0.77 | KIF11 (0.50) | KIF11RAB9AMAPTPTGESCYP2C9 | |
| SCHEMBL27410225 | 0.73 | DAO (0.49) | KIF11RAB9AMAPTPTGESCYP2C9 | |
| SCHEMBL27388577 | 0.73 | PTGS2 (0.53) | KIF11RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL27413780 | 0.71 | KIF11 (0.46) | ARKIF11RAB9AMAPTPOLB | |
| SCHEMBL27409224 | 0.71 | KIF11 (0.44) | KIF11RAB9AMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561252-A1 | 2-Oxoquinoline derivatives as angiotensin II antagonists | MERCK PATENT GmbH (DE) | 1993-09-22 | — | — | EP | disclosed |