Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9567087 | 0.87 | CHRM1 (0.32) | CHRM1FAAHCYP19A1 | |
| SCHEMBL9596282 | 0.83 | MMP2 (0.34) | FAAHCYP19A1 | |
| SCHEMBL9567171 | 0.83 | MMP2 (0.34) | FAAHCYP19A1 | |
| SCHEMBL9567186 | 0.82 | FAAH (0.32) | CHRM1FAAHCYP19A1 | |
| SCHEMBL7233850 | 0.79 | ATM (0.50) | POLBCHRM1CYP19A1ATM | |
| SCHEMBL5494161 | 0.79 | ATM (0.50) | POLBCHRM1CYP19A1ATM | |
| SCHEMBL7597723 | 0.79 | ATM (0.50) | POLBCHRM1CYP19A1ATM | |
| SCHEMBL9328664 | 0.79 | ATM (0.50) | POLBCHRM1CYP19A1ATM | |
| SCHEMBL8547165 | 0.79 | ATM (0.50) | POLBCHRM1CYP19A1ATM | |
| SCHEMBL8582244 | 0.78 | ALDH1A1 (0.48) | POLBCYP19A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993001192-A1 | 2-(2-SUBSTITUTED PYRROLIDINYLTHIO)CARBAPENEM DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-01-21 | — | — | WO | disclosed |
| EP-0522504-A1 | 2-(2-substituted pyrrolidinylthio)-carbapenem derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1993-01-13 | — | — | EP | disclosed |