Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.42 |
| ▸ | KDM5A | P29375 | 2/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.42 |
| ▸ | PTGIR | P43119 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568026 | 0.88 | MEN1 (0.51) | MEN1KMT2ADHODHL3MBTL1HTT | |
| SCHEMBL9568036 | 0.81 | ALDH1A1 (0.50) | MEN1KMT2ADHODHL3MBTL1HTT | |
| SCHEMBL9047770 | 0.80 | PTGIR (0.70) | MEN1KMT2ASIGMAR1KDM4CPTGIR | |
| SCHEMBL5623941 | 0.78 | HTR6 (0.51) | HTTTRPV1KDM4CKDM5AKDM5B | |
| SCHEMBL9567987 | 0.76 | ALDH1A1 (0.49) | MEN1KMT2ADHODHL3MBTL1HTT | |
| SCHEMBL9567963 | 0.76 | ALDH1A1 (0.44) | KMT2ADHODHL3MBTL1HTTALDH1A1 | |
| SCHEMBL9568077 | 0.76 | TRPV1 (0.46) | DHODHL3MBTL1HTTALDH1A1TRPV1 | |
| SCHEMBL9568020 | 0.76 | MEN1 (0.48) | MEN1KMT2AALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL1566782 | 0.76 | SIGMAR1 (0.49) | ALDH1A1TRPV1SIGMAR1 | |
| SCHEMBL5622296 | 0.74 | KDM4C (0.54) | MEN1KMT2AL3MBTL1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |