Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | CFD | P00746 | 2/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047990 | 0.82 | EPHX1 (0.36) | TRPM8EPHX1CHRM1 | |
| SCHEMBL9567976 | 0.81 | TRPM8 (0.47) | TRPM8EPHX1HTTEPHX2KMT2A | |
| SCHEMBL9047991 | 0.80 | PTGIR (0.38) | TRPM8EPHX1 | |
| SCHEMBL9567968 | 0.76 | TRPM8 (0.49) | TRPM8HTTHAO1ALDH1A1 | |
| SCHEMBL9567950 | 0.75 | TRPM8 (0.48) | TRPM8HTTALDH1A1 | |
| SCHEMBL27385115 | 0.74 | TRPM8 (0.43) | TRPM8EPHX1EPHX2 | |
| SCHEMBL2406499 | 0.71 | HTT (0.45) | TRPM8HTTALDH1A1 | |
| SCHEMBL5198565 | 0.71 | TRPM8 (0.44) | TRPM8HTTALDH1A1 | |
| SCHEMBL8515492 | 0.70 | TAOK1 (0.42) | TRPM8EPHX2PSMB5ALDH1A1 | |
| SCHEMBL30644032 | 0.70 | HTT (0.48) | TRPM8EPHX1HTTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |