Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.39 |
| ▸ | KDM5A | P29375 | 2/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | CFD | P00746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048510 | 0.82 | PTGIR (0.36) | TRPM8EPHX1PARP1PARP2KDM4C | |
| SCHEMBL9568004 | 0.81 | TRPM8 (0.48) | TRPM8EPHX1HTTEPHX2KMT2A | |
| SCHEMBL9048514 | 0.80 | PTGIR (0.42) | EPHX1KDM4C | |
| SCHEMBL9568075 | 0.76 | TRPM8 (0.48) | TRPM8HTTPARP1PARP2KDM4C | |
| SCHEMBL9568024 | 0.76 | KDM4C (0.48) | TRPM8PARP1PARP2KDM4CKDM5A | |
| SCHEMBL9568022 | 0.75 | ALDH1A1 (0.52) | TRPM8EPHX1HTTPARP1PARP2 | |
| SCHEMBL9568032 | 0.75 | TRPM8 (0.47) | TRPM8PARP1PARP2KDM4CKDM5A | |
| SCHEMBL5444606 | 0.73 | TRPM8 (0.45) | TRPM8HTTPARP1PARP2KDM4C | |
| SCHEMBL9568008 | 0.73 | ALDH1A1 (0.51) | HTTKDM4CKDM5AKDM5BPDPK1 | |
| SCHEMBL9567999 | 0.72 | TRPM8 (0.47) | TRPM8HTTPARP1PARP2KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |