Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | ECE1 | P42892 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CTSV | O60911 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9567968 | 0.89 | TRPM8 (0.49) | TRPM8MTNR1BECE1HTTALDH1A1 | |
| SCHEMBL2406499 | 0.82 | HTT (0.45) | TRPM8ECE1HTTALDH1A1BLM | |
| SCHEMBL5198565 | 0.82 | TRPM8 (0.44) | TRPM8ECE1HTTALDH1A1BLM | |
| SCHEMBL9050469 | 0.81 | KMT2A (0.36) | TRPM8ALDH1A1 | |
| SCHEMBL9568032 | 0.79 | TRPM8 (0.47) | TRPM8MTNR1BBLM | |
| SCHEMBL9048588 | 0.78 | PTGIR (0.54) | — | |
| SCHEMBL11073296 | 0.75 | ECE1 (0.45) | ECE1HTTALDH1A1BLM | |
| SCHEMBL9568005 | 0.75 | TRPM8 (0.39) | TRPM8MTNR1B | |
| SCHEMBL8802816 | 0.75 | TSHR (0.50) | ECE1HTTALDH1A1BLM | |
| SCHEMBL9568004 | 0.75 | TRPM8 (0.48) | TRPM8HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |