Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | FCER2 | P06734 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | PTGIR | P43119 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 4/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | TPH1 | P17752 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050999 | 0.81 | PTGIR (0.48) | PTGIR | |
| SCHEMBL9567999 | 0.77 | TRPM8 (0.47) | TRPM8 | |
| SCHEMBL9567947 | 0.76 | TRPM8 (0.39) | MMP1FCER2MMP9MMP3TRPM8 | |
| SCHEMBL9567949 | 0.70 | ALDH1A1 (0.50) | PTGIRPREPDGAT1 | |
| SCHEMBL7809851 | 0.70 | MMP1 (0.52) | MMP1FCER2MMP9MMP3PPARG | |
| SCHEMBL6571514 | 0.70 | MMP1 (0.52) | MMP1FCER2MMP9MMP3PPARG | |
| SCHEMBL6571517 | 0.70 | MMP1 (0.52) | MMP1FCER2MMP9MMP3PPARG | |
| SCHEMBL6573689 | 0.70 | MMP1 (0.52) | MMP1FCER2MMP9MMP3PPARG | |
| SCHEMBL30612420 | 0.70 | PREP (0.51) | CYP19A1PREPNPY1RNPY5R | |
| SCHEMBL1726797 | 0.70 | PREP (0.51) | CYP19A1PREPNPY1RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | claimed |
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |