Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568103 | 0.82 | SMN1; SMN2 (0.42) | HTR2BSMN1; SMN2 | |
| SCHEMBL9568090 | 0.82 | ITGB3 (0.41) | POLBTGM2HTR2BLMNA | |
| SCHEMBL9568118 | 0.80 | POLB (0.45) | POLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8407956 | 0.72 | ITGB3 (0.44) | POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL8407957 | 0.72 | POLB (0.43) | POLBHTR2BLMNASMN1; SMN2HTR1A | |
| SCHEMBL8410914 | 0.72 | ITGB3 (0.42) | POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL8407202 | 0.71 | YAP1 (0.49) | POLBTGM2HTR2BLMNASMN1; SMN2 | |
| SCHEMBL9568217 | 0.70 | HRH3 (0.42) | POLBHTR2BSMN1; SMN2ALDH1A1 | |
| SCHEMBL9568105 | 0.70 | ITGB3 (0.43) | POLBHTR2BLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9568095 | 0.70 | TGM2 (0.48) | POLBTGM2HTR2BLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574808-A1 | Amidine-biphenyl derivatives, process for their production & medical preparation containing them | Dr. Karl Thomae GmbH (DE) | 1993-12-22 | — | — | EP | disclosed |