Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | GNRHR | P30968 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568459 | 0.91 | PRKCZ (0.44) | PRKCZKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL9568395 | 0.89 | KDM4E (0.44) | KDM4EALDH1A1HPGDMEN1GAA | |
| SCHEMBL9568435 | 0.87 | PRKAB2 (0.36) | — | |
| SCHEMBL9568298 | 0.83 | LMNA (0.39) | PRKCZKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL9568392 | 0.83 | PRKCZ (0.35) | PRKCZKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL9568351 | 0.81 | PRKCZ (0.37) | PRKCZKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL10744715 | 0.80 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDKMT2AHSD17B10 | |
| SCHEMBL9568345 | 0.79 | PRKCZ (0.42) | PRKCZKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL9568405 | 0.79 | PRKCZ (0.40) | PRKCZKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL9568318 | 0.79 | ALDH1A1 (0.38) | PRKCZKDM4EALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551518-A1 | QUINOLINECARBOXYLIC ACID DERIVATIVE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-07-21 | — | — | EP | disclosed |