Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ME2 | P23368 | 5/20 | 1.00 |
| ▸ | ME1 | P48163 | 5/20 | 1.00 |
| ▸ | ME3 | Q16798 | 5/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.78 |
| ▸ | MEN1 | O00255 | 2/20 | 0.78 |
| ▸ | GFER | P55789 | 2/20 | 0.77 |
| ▸ | ATM | Q13315 | 1/20 | 0.77 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | GRM5 | P41594 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23244396 | 0.93 | ME2 (0.86) | ME2ME1ME3KMT2AMEN1 | |
| SCHEMBL11076871 | 0.87 | GFER (0.89) | ME2ME1ME3KMT2AMEN1 | |
| SCHEMBL10902216 | 0.86 | GFER (0.78) | ME2ME1ME3KMT2AMEN1 | |
| SCHEMBL23244223 | 0.85 | ME3 (1.00) | ME2ME1ME3KMT2AMEN1 | |
| SCHEMBL23244286 | 0.82 | ME2 (1.00) | ME2ME1ME3KMT2AMEN1 | |
| SCHEMBL29666895 | 0.82 | ME2 (0.69) | ME2ME1ME3KMT2AMEN1 | |
| SCHEMBL9568359 | 0.81 | ME2 (0.67) | ME2ME1ME3KMT2AMEN1 | |
| SCHEMBL5539457 | 0.79 | ME2 (0.63) | ME2ME1ME3KMT2AMEN1 | |
| SCHEMBL23244264 | 0.79 | ME2 (0.78) | ME2ME1ME3KMT2AMEN1 | |
| SCHEMBL10981623 | 0.79 | ME2 (0.64) | ME2ME1ME3KMT2AGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1627871-B1 | CYCLIC AMINOPHENYL SULFAMATE DERIVATIVE | ASKA PHARM CO LTD (JP) | 2010-04-14 | — | — | EP | disclosed |
| CN-100467449-C | Cyclic aminophenyl sulfamate derivative | ASKA PHARM CO LTD (JP) | 2009-03-11 | — | — | CN | disclosed |
| US-7449466-B2 | Cyclic aminophenyl sulfamate derivative | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2008-11-11 | — | — | US | disclosed |
| US-20060189625-A1 | Cyclic aminophenyl sulfamate derivative | ASKA PHARMACEUTICAL CO., LTD. (JP) | 2006-08-24 | — | — | US | disclosed |
| CN-1823039-A | Cyclic aminophenyl sulfamate derivative | ASKA PHARM CO LTD (JP) | 2006-08-23 | — | — | CN | disclosed |
| EP-1627871-A1 | CYCLIC AMINOPHENYL SULFAMATE DERIVATIVE | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2006-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189625-A1 | Cyclic aminophenyl sulfamate derivative | SHBG, STS, ARSA | ME2 976/4885ME1 746/4885ME3 400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.