Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.53 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ME2 | P23368 | 1/20 | 0.46 |
| ▸ | ME1 | P48163 | 1/20 | 0.46 |
| ▸ | ME3 | Q16798 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321206 | 0.86 | THRB (0.64) | KMT2ACACNA1GKCNH2TP53ALDH1A1 | |
| SCHEMBL9321204 | 0.84 | GPR183 (0.56) | KMT2ACACNA1GTP53CHRM1HTR2A | |
| SCHEMBL9568359 | 0.84 | ME2 (0.67) | KMT2ACACNA1GALDH1A1MAPTGFER | |
| SCHEMBL9321227 | 0.81 | POLB (0.49) | KMT2ACACNA1GHTR1ADRD2TP53 | |
| SCHEMBL9568289 | 0.80 | CACNA1G (0.57) | KMT2ACACNA1GDRD2TP53ALDH1A1 | |
| SCHEMBL9568292 | 0.79 | SIGMAR1 (0.56) | KMT2ACACNA1GDRD2TP53ALDH1A1 | |
| SCHEMBL9568368 | 0.78 | LMNA (0.58) | KMT2AKCNH2HTR1ADRD2MAPT | |
| SCHEMBL9319916 | 0.78 | THRB (0.61) | KMT2ACACNA1GKCNH2TP53ALDH1A1 | |
| SCHEMBL9426171 | 0.76 | THRB (0.63) | KMT2ACACNA1GKCNH2TP53ALDH1A1 | |
| SCHEMBL9322289 | 0.76 | CACNA1G (0.60) | KMT2ACACNA1GKCNH2DRD2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524146-A1 | Aminosubstituted Piperazinederivatives | CIBA-GEIGY AG (CH) | 1993-01-20 | — | — | EP | disclosed |